Term
Cause
Effect (Symptom)
Addison's Syndrome
Inadequate secretion of coricosteroid
hormones by the adrenal glands,
sometimes as a result of tuberculous
infection.
Symptoms include weakness, loss of
energy, low blood pressure, and dark
pigmentation of the skin.
Amenorrhoea
Primary amenorrhoea (menstrual periods
fail to appear at puberty) may be caused
by absence of the uterus or ovaries (e.g.
Turner’s syndrome) or a hormonal
imbalance.

Secondary amenorrhoea (menstrual
periods stop after establishment of
puberty) may be caused by disorders of
the hypothalamus, deficiency of ovarian,
pituitary, or thyroid hormones, mental
disturbance, depression, anorexia
nervosa, or a major change of
surroundings or circumstances.
The absence or stopping of the menstrual
periods. (It is normal for the periods to be
absent before puberty, during pregnancy
and milk secretion, and after the end of
the reproductive period.)
Cushing's Syndrome
Excess amounts of cortico-steroid
hormones in the body.
Symptoms include: weight gain; reddening
of the face and neck; excess growth of
body and facial hair; raised blood
pressure; loss of mineral from the bones
(osteoporosis); raised blood glucose
levels; and sometimes mental
disturbances.
Menopause
Cessation of viable egg production in the
female.
Leads to hormonal imbalance; lack of
negative feedback to the
hypothalamus/activity; continued release
of FSH. Symptoms: hot flushes; night
sweats; mood swings; increased risk of
heart attack; osteoporosis speeds up.
Pre-menstrual Syndrome
Associated with the accumulation of salt
and water in tissues.
The hormone progesterone is thought to
be a causative element and a deficiency
of fatty acids has also been observed.
Nervousness; irritability; emotional
disturbance; headache; and/or
depression – said to affect some women
for up to about 10 days prior to
menstruation.
Polycystic Ovarian Syndrome
A hormonal disorder characterized by
incomplete development of Graafian
follicles in the ovary due to inadequate
secretion of luteinizing hormone; the
follicles fail to ovulate and remain as
multiple cysts distending the ovary.
Further hormone imbalance results in
obesity, hirsutism and acne and the
woman is infertile due to the lack of
ovulation.
Diabetes

(click here  for more on
Diabetes)
Diabetes is a condition related to the
ability of the body to regulate the amount
of sugar (glucose) in the blood.
This is usually regulated by the hormone
insulin, which is produced and secreted
by the Beta cells (B-cells) of the
pancreas.
"Hypo" refers to there being less than 3.5
m.mol/litre (of glucose) per litre of blood.
Symptoms may include sweating, shakes
and light-headedness.
If the level continues to drop then the
person may fall into a coma. If it drops still
further, death may result.
Hyper" refers to there being more than
10.1 m.mol/litre (of glucose) per litre of
blood. Symptoms may include urination,
headaches, blurred vision and
keto-acidosis. If the level continues to
increase then the person may fall into a
coma. If it increases still further, then
death may result.
The following table lists some common endocrine conditions:
Endocrine Conditions